{"id":39011,"date":"2021-06-17T09:38:31","date_gmt":"2021-06-17T09:38:31","guid":{"rendered":"https:\/\/solidaridadintergeneracional.es\/wp\/?p=39011"},"modified":"2021-06-17T09:38:31","modified_gmt":"2021-06-17T09:38:31","slug":"identifican-la-presencia-de-alzheimer-anos-antes-de-los-sintomas","status":"publish","type":"post","link":"https:\/\/solidaridadintergeneracional.es\/wp\/identifican-la-presencia-de-alzheimer-anos-antes-de-los-sintomas\/","title":{"rendered":"Identifican la presencia de Alzheimer a\u00f1os antes de los s\u00edntomas."},"content":{"rendered":"
La mayor\u00eda de las personas con Alzheimer son mayores de 65 a\u00f1os.<\/h5>\n

Ep<\/p>\n

Enlace noticia original<\/a><\/p>\n

Un nuevo estudio ha demostrado que un novedoso\u00a0radiotrazador de tomograf\u00eda por emisi\u00f3n de positrones (PET)\u00a0<\/strong>mide eficazmente los aumentos de tau en el cerebro, una caracter\u00edstica distintiva del\u00a0<\/a>Alzheimer,<\/strong>\u00a0antes de que se observen los s\u00edntomas de la enfermedad. Esta investigaci\u00f3n se present\u00f3 en la\u00a0Reuni\u00f3n Anual de la\u00a0Sociedad de Medicina Nuclear e Imagen Molecular 2021.<\/strong><\/p>\n

Con la posibilidad de medir el\u00a0aumento de tau<\/strong>\u00a0durante un largo periodo de tiempo, este trazador ofrece una importante herramienta para\u00a0evaluar la eficacia de los tratamientos de la enfermedad de Alzheimer\u00a0<\/strong>en los ensayos cl\u00ednicos.<\/p>\n

Tau es una\u00a0prote\u00edna que se encuentra habitualmente en las neuronas cerebrales<\/strong>\u00a0sanas. En las personas con ciertos trastornos cerebrales, como la enfermedad de Alzheimer, los cambios qu\u00edmicos\u00a0hacen que las prote\u00ednas tau se acumulen en varias partes del cerebro.<\/strong>\u00a0Por ello, la prote\u00edna tau es un valioso biomarcador para medir la progresi\u00f3n de la enfermedad.<\/p>\n

En el estudio, los investigadores trataron de\u00a0detectar patrones y tasas de acumulaci\u00f3n de tau\u00a0<\/strong>tanto en una poblaci\u00f3n que envejece con normalidad cognitiva como en aquellos que padecen la enfermedad de Alzheimer. Se realizaron im\u00e1genes PET con el\u00a0nuevo radiotrazador 18F-MK6240<\/strong>\u00a0en todos los participantes al inicio y despu\u00e9s de 12 meses. Despu\u00e9s de cada exploraci\u00f3n, se midi\u00f3 la\u00a0captaci\u00f3n del radiotrazador en m\u00faltiples \u00e1reas del cerebro.<\/strong><\/p>\n

Se midi\u00f3 el aumento de tau en ambos grupos de participantes<\/strong><\/p>\n

Las im\u00e1genes longitudinales de tau fueron eficaces para discriminar entre las dos cohortes. La captaci\u00f3n de\u00a018F-MK6240\u00a0<\/strong>fue mayor en la l\u00ednea de base y despu\u00e9s de un a\u00f1o en los participantes que\u00a0se encontraban en el continuo de la enfermedad de Alzheimer<\/strong>\u00a0en comparaci\u00f3n con los participantes con\u00a0envejecimiento cognitivo normal.<\/strong><\/p>\n

“La eficacia del trazador 18F-MK6240 es importante para los ensayos farmacol\u00f3gicos que\u00a0pretenden medir si los tratamientos para eliminar la tau del cerebro est\u00e1n funcionando realmente”,<\/strong>\u00a0explica Christopher Rowe, director de investigaci\u00f3n de im\u00e1genes moleculares en Austin Health y director de la Red Australiana de Demencia en Melbourne, en Australia.<\/p>\n

“El uso de la radiosonda permitir\u00e1 a los investigadores\u00a0seleccionar a personas en distintas fases de la enfermedad de Alzheimer<\/strong>\u00a0para realizar ensayos cl\u00ednicos, lo que en \u00faltima instancia podr\u00eda\u00a0acelerar el desarrollo de tratamientos eficaces para la enfermedad”<\/strong>, a\u00f1ade.<\/p>\n","protected":false},"excerpt":{"rendered":"

La mayor\u00eda de las personas con Alzheimer son mayores de 65 a\u00f1os.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[324,327,328],"tags":[],"class_list":["post-39011","post","type-post","status-publish","format-standard","hentry","category-lasaludysucuidado","category-mayores","category-noticiasboletin"],"yoast_head":"\nIdentifican la presencia de Alzheimer a\u00f1os antes de los s\u00edntomas. – Solidaridad Intergeneracional<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/solidaridadintergeneracional.es\/wp\/identifican-la-presencia-de-alzheimer-anos-antes-de-los-sintomas\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" 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